uk map with pointers

Manchester Academic Health Sciences Centre Trials Unit (MAHSC-CTU)
Liverpool Cancer Research UK Clinical Trials Unit (LCTU), Liverpool
Cancer Research UK Clinical Trials Unit (CRCTU), Birmingham
Warwick Clinical Trials Unit
Wales Cancer Trials Unit (WCTU), Cardiff
Bristol Randomised Trials Collaboration (BRTC)
Oxford Clinical Trials Research Unit (OCTRU)
Southampton Clinical Trials Unit
Institute of Cancer Research Clinical Trials and Statistics Unit (ICR-CTSU), Sutton
Cancer Prevention Trials Unit at Barts CTU, London
Medical Research Council Clinical Trials Unit (MRC CTU at UCL), London
Cancer Research UK & University College London Cancer Trials Centre (CRUK & UCL CTC), London
Cambridge Clinical Trials Unit, Cambridge
Clinical Trials Research Unit (CTRU), Leeds
Cancer Clinical Trials Unit Scotland (CaCTUS), Edinburgh
Cancer Clinical Trials Unit Scotland (CaCTUS), Glasgow
Click on a CTU to display more information.
Name of CTU URL Specialisms* Directors Group Representative* Operations Leads Group Representative*
Liverpool Cancer Research UK Clinical Trials Unit (LCTU), Liverpool Click here to visit their website Disease areas:

  • Pancreatic
  • Haemato-oncology
  • Hepatobiliary
  • Urology
  • Breast
  • Palliative Care
  • Head and Neck
  • Uveal Melanoma

Therapeutic areas:

  • Chemotherapy
  • Neoadjuvant and Adjuvant therapies
  • Targeted treatments
  • Predictive Biomarkers
  • Imaging technologies
  • Immunotherapy
  • Surgery
  • Radiotherapy technologies

Methodological areas:

  • Information Systems – Development and Management of IS systems for clinical trials
  • Statistics and Bioinformatics – Clinical Trial Design and Methodology, Analytical Methods
  • Phase III Study – extensive experience in designing and conducting PHASE III RCTs
  • Translational sub-studies
  • GCP Labs and Biobanking
Professor John Neoptolemos Charlotte Rawcliffe
Manchester Academic Health Sciences Centre Trials Unit (MAHSC-CTU) Click here to visit their website Disease areas:

  • Breast
  • Lung
  • Colorectal
  • Prostate
  • Bladder
  • Head and neck
  • Melanoma

Therapeutic areas:

  • Targeted treatments
  • Radiotherapy technologies
  • Predictive biomarkers

Methodological areas:

  • Biomarker evaluation
  • Trial conduct (including accrual, retention, data monitoring)
  • Early phase trial design
Mr Philip Barley  TBC
Cancer Research UK Clinical Trials Unit (CRCTU), Birmingham Click here to visit their website Disease areas:

  • Breast
  • Lung
  • Head and neck
  • Hepatobiliary
  • Skin
  • Haematological malignancies
  • Paediatric cancers

Therapeutic areas:

  • Targeted/stratified medicine
  • Multi-modality treatment trials including surgery and radiotherapy

Methodological areas:

  • International
  • Early phase
  • Late phase
  • Bayesian
  • Adaptive design
Professor Pamela Kearns Dr Sarah Bowden
Warwick Clinical Trials Unit Click here to visit their website Disease Areas

  • Breast
  • Head & Neck
  • Upper GI
  • Myeloma
  • Bladder
  • Prostate

Therapeutic Areas

  • Supportive care
  • Predictive biomarkers
  • Targeted treatments
  • Radiotherapy

Methodological Areas

  • Large complex trials
  • Translational sub-studies
  • Clinical trial statistics & methodology
  • Health Economics
  • Quality of Life
  • Qualitative Research
  • PPI
  • Links to systems biology
Professor Janet Dunn Joanne Grumett
Wales Cancer Trials Unit (WCTU), Cardiff Click here to visit their website  TBC Dr Richard Adams Dr Lisette Nixon
Bristol Randomised Trials Collaboration (BRTC) Click here to visit their website Disease areas:

  • Prostate

Methodological areas:

  • Complex interventional trials
  • Qualitative research to understand trial recruitment and conduct
Dr Athene Lane Mrs Jo Simon
Oxford Clinical Trials Research Unit (OCTRU) Click here to visit their website  TBC Professor Tim Maughan Sarah Pearson
Southampton Clinical Trials Unit Click here to visit their website Disease areas:

  • Lymphoid malignancy
  • Thoracic malignancy
  • Upper GI
  • Urology
  • Head & neck
  • Colorectal

Therapeutic areas:

  • Immunotherapy
  • Surgery
  • Chemotherapy
  • Supportive care
  • Primary care oncology
  • Early diagnosis
Professor Gareth Griffiths Jane Robertson
Institute of Cancer Research Clinical Trials and Statistics Unit (ICR-CTSU), Sutton Click here to visit their website Disease areas:

  • Breast
  • Prostate
  • Bladder
  • Penile
  • Head and neck
  • Melanoma
  • Lung
  • Rare cancers

Therapeutic areas:

  • Systemic therapies
  • Targeted treatments
  • Radiotherapy technologies
  • Predictive biomarkers

Methodological areas:

  • Biomarker evaluation
  • Patterns of disease relapse
  • Use of routinely available data
Professor Judith Bliss Claire Snowdon
Cancer Prevention Trials Unit at Barts CTU, London Click here to visit their website Disease areas:

  • Breast
  • Cervix
  • Colorectal
  • Head and neck
  • Oesophageal
  • Prostate

Therapeutic areas:

  •  Chemoprevention
  • Screening
  • Hormonal therapy
  • Aspirin
  • Vitamin D
  • Smoking cessation interventions
  • Surgery
  • Devices
  • Exercise

Please note that we would like to make it clear that our unit is not involved in these therapeutic areas: “NOT chemotherapy”, “NOT radiotherapy” and “NOT immunotherapy”

Methodological areas:

  • Use of routinely available data
  • International trials
  • Factorial designs
  • Cluster randomisation
  • Remote monitoring
Professor Peter Sasieni Benoit Aigret
Medical Research Council Clinical Trials Unit (MRC CTU at UCL), London Click here to visit their website Disease areas:

  • Prostate
  • Renal
  • Colorectal
  • Ovarian
  • Testis
  • Brain
  • Upper GI cancers
  • Viral-related malignancies

Therapeutic areas:

  • Re-purposed agents

Methodology areas:

  • International collaboration or with special relevance in the developing world
  • Development and conduct of new trial designs for late clinical trials
  • Biomarker-stratified or precision medicine trials
  • Platform trials
  • Multi-arm, multi-stage trials
Professor Rick Kaplan Dr Claire Amos
Cancer Research UK & University College London Cancer Trials Centre (CRUK & UCL CTC), London Click here to visit their website Disease areas:

  • Head and neck
  • Haematology
  • Brain
  • Upper and lower gastrointestinal tract
  • Gynaecology
  • Lung
  • Sarcoma
  • Rare cancers

Therapeutic areas:

  • Chemotherapy
  • Advanced therapies (gene therapies, cell therapies, vaccines)
  • Radiotherapy (including stereotactic ablative radiotherapy)
  • Surgery
  • Targeted treatments (antibodies and small molecules)
  • Multimodality treatments
  • Diagnosis
  • Screening

Methodological areas:

  • Prognostic and predictive biomarker evaluation
  • Dose escalation trials using Bayesian methods
  • Central data monitoring
  • Systematic reviews
Professor Jonathan Ledermann Nicole Gower
Cambridge Clinical Trials Unit Click here to visit their website  Disease areas:

  • Aerodigestive (lung, upper GI, colorectal etc.
  • Breast
  • CNS
  • Haematology
  • Melanoma
  • Ovary
  • Pancreas
  • Urology (kidney, prostate etc.)

Therapeutic areas:

  • Biomarkers
  • Novel therapeutics, inc. immunotherapies
  • Radiotherapy
  • Molecular Imaging
Professor Duncan Jodrell Si-Houy Lao-Sirieix
Clinical Trials Research Unit (CTRU), Leeds Click here to visit their website Disease areas:

  • Haematology
  • Colorectal
  • Hepatobiliary
  • Urology
  • Breast
  • Melanoma

Therapeutic areas:

  • Systemic therapies (including chemotherapies and targeted therapies)
  • Radiotherapy
  • Surgical technologies
  • Predictive biomarkers

Methodological areas:

  • Biomarker evaluation
  • Patterns of disease relapse
  • Use of routinely available data
  • Early phase designs
  • Adaptive and rolling trial designs
Professor Julia Brown Alex Smith/Vicky Hiley
Cancer Clinical Trials Unit Scotland (CaCTUS), Edinburgh Click here to visit their website Disease areas:

  • Breast
  • Lung
  • Renal
  • Neuro-oncology
  • Metastatic disease

Therapeutic areas:

  • Practice changing phase III trials
  • Imaging
  • Radiotherapy

Methodological areas:

  • Quality of Life trials
  • Phase II/III
Julie Uttridge Julie Uttridge
Cancer Clinical Trials Unit Scotland (CaCTUS), Glasgow Click here to visit their website Disease areas: 

  • Gastrointestinal (colorectal cancer, pancreatic ductal adenocarcinoma (PDAC), gastroesophageal cancer)
  • Gynaecology
  • Urology (prostate, bladder and kidney)
  • Lung cancer
  • Chronic Myeloid Leukemia
  • Rare cancers (including Central Nervous System (CNS) and International Rare Cancers Initiative (IRCI))

Therapeutic areas:

  • Translational studies
  • Early development of novel investigational medicinal products
  • Practice changing phase III trials

Methodological areas:

  • Stratified medicine trials
  • Phase I / II
Dr Rob Jones Andrea Harkin