B169
A comparison of incidence trends of melanoma and cancer of the cervix in teenagers and young adults with older adults
Robert Alston1, Marco Geraci1, Tim Eden1, Anthony Moran2, Steven Rowan3, Jillian Birch1
1University of manchester, Manchester, UK, 2North West Cancer Intelligence Service, Christie Hospital, Manchester, UK, 3National Cancer intelligence service, London, UK
Background
Although most cases of melanoma and cancer of the cervix occur in older cases these are numerically important in TYAs. The aims were to compare incidence trends of melanoma and cervix carcinoma by age for individuals under the age of 40.
Method
Anonymised individual level national cancer registrations for England, 1979 to 2003 were supplied by the Office for National Statistics. Incidence rates were calculated and compared using a generalised linear model.
Results
The rate of melanoma was from 9.2 per million person years at risk (pmyr) in 15-19 year olds and increased with age to 81.1 pmyr in 35-39 year olds. The rate increased over time in 15-39 year olds from 28.9 pmyr in 1979-1983 to 59.9 in 1999-2003. The annual rate of increase was greatest among 20-29 year olds (4.0%) and but only 2.5% in 30-39 year olds. Cervical carcinoma rates in 15-19 year olds increased from 0.2 pmyr in 1979-1983 to 1.6 pmyr in 1997-2003 and in 20-24 year olds it increased from 20.4 pmyr to 27.5 pmyr. It decreased in 35-39 year olds from 203.5 pmyr to 155.7 pmyr over the same period.
Conclusion
Cancer incidence patterns for two of the most easily prevented cancers that are common in teenagers and young adults are different from those seen in slightly older adults.
Acknowledgments
Data used in this study were contributed by the nine regional cancer registries in England. The research was funded by Cancer Research UK and CLIC Sargent.
