C109
Prostate cancer treatment and survival by ethnic group in South East England
Ruth Jack, Elizabeth Davies, Henrik Møller
King's College London, London, UK
Background
Although US studies have examined prostate cancer patients’ treatment and survival in different ethnic groups, little work has been done so far in the UK.
Method
Data on 36,961 men resident in South East England diagnosed with prostate cancer between 1998 and 2004 were extracted from the Thames Cancer Registry. The ethnic groups examined were White (n=19,688), Black (n=1,422) and Indian/Pakistani (n=397). Logistic regression was used to describe whether patients received cancer surgery, hormone therapy or radiotherapy within six months of diagnosis, adjusted for age, socioeconomic deprivation and stage. To assess prostate cancer-specific survival, Cox regression models were fitted, adjusting for age, socioeconomic deprivation, stage and treatment received.
Results
White men were significantly more likely to receive cancer surgery (10%) and hormone therapy (44%) than Indian/Pakistani (7%, p=0.036; 37%, p=0.012) or Black (8%, p=0.035; 38%, p<0.001) men. There was no difference in the proportion of men receiving radiotherapy. Indian/Pakistani men had better prostate cancer-specific survival than White men (hazard ratio [HR]=0.76, p=0.024). There was no difference in survival in Black compared to White men (HR=0.93, p=0.238).
Conclusion
Although Black men have higher prostate cancer incidence rates than other ethnic groups, and they are less likely to receive curative surgery and hormone therapy, their survival is no worse. Indian/Pakistani men are also less likely to receive surgery and hormone therapy, but have better prostate cancer-specific survival than White men.
