Targeting mitosis
- Introduction: Targeting mitosis
- Small molecule inhibitors of mitotic progression
- Probing the mechanism of novel drugs targeted to mitosis in pre-clinical studies
- Early clinical studies with anti-mitotic agents
- p53 prevents entry into mitosis with uncapped telomeres
- Physicochemical and pharmacological determinants of the efficacy of a novel series of CDK7 inhibitors
- Loss of a FOX03A-dependent cell cycle checkpoint for DNA replication origins sensitises cancer cells to CDC7 inhibitors
