2006 Poster Abstracts

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A 1H MRS STUDY OF TUMOUR OVEREXPRESSION OF DIMETHYLARGININE DIMETHYLAMINOHYDROLASE (DDAH) AND RESPONSE TO TAXOTERE

Poster No: C150

Authors:
MADHU B, ANSARI S, GRIFFITHS JR, WHITLEY GS, ROBINSON SP

A comparative study of the stability of gene expression profiles built by univariate or multivariate methods and of their dependence on the choice of training data

Poster No: C12

Authors:
ZUCKNICK M., STRONACH E.A., GABRA H., RICHARDSON S.

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A functional analysis of PCNA-binding peptides derived from protein sequence, screening and rational design.

Poster No: A189

Authors:
WARBRICK E

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A genetic screen for novel regulators of cep-1/p53 in C. elegans

Poster No: A114

Authors:
RUTKOWSKI RJ, GARTNER A

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A metabolic study of HIF-2 alpha over-expressing and empty vector 7860 renal tumours using in vivo and in vitro 1H MRS

Poster No: B114

Authors:
TROY H, CHUNG Y-L, MADHU B, HARRIS A.L, WIGFIELD S, BISWAS S, STUBBS M, GRIFFITHS J.R

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A Microarray Screen Identifies Dll4 Target Genes in Endothelial Cells

Poster No: A205

Authors:
HARRINGTON L.S., SAINSON R.C.A., KIMMEL WILLIAMS C, SHI W, LI J-L, HARRIS A.L.

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A New (Bayesian) Classification of Human Breast Cancer

Poster No: C121

Authors:
CAMPBELL C, CARRIVICK L, ROGERS S, CLARK JP, GIROLAMI M, COOPER CS

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A pilot randomised controlled trial of Megestrol Acetate and Prednisolone for anorexia and weight loss in patients with lung cancer or mesothelioma

Poster No: B96

Authors:
CHATTOPADHYAY A, AHMEDZAI S, HORSMAN J, CLARKE R, BIRCH L, SIDDALL V, HATTON M

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A pilot study to determine the accuracy of mouth self-examination in a high risk population

Poster No: CR-UK8

Authors:
SCOTT SE, GRUNFELD EA, MCGURK M, WEINMAN J

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A prospective comparison of health-related quality of life during potentially curative chemoradiation or neoadjuvant treatment and surgery for locally advanced oesophageal cancer

Poster No: A55

Authors:
AVERY KNL, METCALFE C, NICKLIN J, BARHAM CP, ALDERSON D, DONOVAN JL, FALK SJ, BLAZEBY JM

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A prospective study of active surveillance for untreated, localised prostate cancer

Poster No: B33

Authors:
PARKER CC, NORMAN AR, VAN AS N, HORWICH A, HUDDART RA, KHOO VS, THOMPSON A, DEARNALEY DP

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A radiographer-delivered intervention to promote early presentation of breast cancer among women as they leave the routine protection of the NHS Breast Screening Programme

Poster No: A24

Authors:
BURGESS C, OMAR L, BISH A, HUNTER M, SALKOVSKIS P, MICHELL M, KIRBY G, WHELEHAN P, RAMIREZ A

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A randomised controlled trial of relaxation training to reduce hot flushes after breast cancer

Poster No: C114

Authors:
FENLON D.R., CORNER J.C., HAVILAND J.S.

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A Randomised Phase III Trial of Dexamethasone and Aspirin (DA) Versus Dexamethasone, Diethylstilbestrol and Aspirin (DAS) in Locally Advanced or Metastatic Cancer of the Prostate – immediate versus deferred diethylstilbestrol

Poster No: B34

Authors:
SHAMASH JONATHAN, POWLES THOMAS, WILSON PETER, MCFAUL SIOBHAN, ANSELL WENDY, DAVIES ANDREW, WALSH EDWARD, OLIVER TIM

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A randomised trial of the combination of lomeguatrib and temozolomide and temozolomide alone in patients with advanced melanoma.

Poster No: A138

Authors:
MIDDLETON M, RANSON M, HERSEY P, BEITH J, THOMPSON D, MORTIMER P, MARGISON G

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A recombinant antibody-enzyme fusion protein produced in Pichia pastoris in compliance with EU Clinical Trials Directive for Phase I/II cancer trials

Poster No: A178

Authors:
TOLNER B, HILLYER T, SMITH L, BEGENT RHJ, CONTRERAS R, CHESTER KA

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A review of research-related information requests to a cancer registry over the past 5 years

Poster No: C11

Authors:
DEVRELL C

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A study investigating the potential benefits to young women (aged 18-45 years) with breast cancer participating in the Younger Women’s Forum – a psycho-educational intervention.

Poster No: A1

Authors:
SCANLON KA, TILKI SS

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A Study of the Effect of Ethnicity on Prostate Cancer Familiality and Survival of Men with Prostate Cancer in the United Kingdom.

Poster No: B46

Authors:
GUY M, SOUTHGATE C, O'BRIEN L, HALL A, GEHR-SWAIN B, WILKINSON R, NORMAN A, DEARNALEY DP, KHOO VS, PARKER CC, HUDDART RA, HORWICH A, FALCONER A, EELES RA

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A STUDY TO ASSESS THE BENEFITS OF COGNITIVE BEHAVIOURAL THERAPY TO MAINTAIN PSYCHOLOGICAL WELL BEING IN A GROUP OF ONCOLOGISTS

Poster No: A25

Authors:
MCKINNA F.E., MARIEN B, BLOOMFIELD D, CHALMERS A, DEUTSCH G, BASSAN J, HIERSCHE A, MITRA S, NEWMAN G, SIMCOCK R, SIMPSON J, WEBB A, WILKINS M, WILLIAMS C

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A survey of alternative therapies in chemotherapy patients-cancer centre study

Poster No: A20

Authors:
HATCHER HM, PALMER CA, HORAN G, SIMPSON N, EARL HM

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A THEORETICAL ANALYSIS OF THE INTERACTIONS BETWEEN BETA-CATENIN’S ADHESIVE AND TRANSCRIPTIONAL FUNCTIONS

Poster No: B116

Authors:
VAN LEEUWEN I.M.M., BYRNE H.M., JENSEN O.E., KING J.R.

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A written emotional expression intervention for women who have completed treatment for breast cancer: effects on perceived emotional support.

Poster No: C80

Authors:
GELLAITRY G, PETERS K, BLOOMFIELD D, HORNE R

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Aberrant CpG island methylation is potentially both an early diagnostic and predictive marker of ovarian cancer

Poster No: BOA6

Authors:
HARDIE C, TEODORIDIS J.M, HALL J, CURTO J, SIDDIQUI N, BROWN R

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Absence of Peroxisome Proliferator Activated Receptor-a (PPAR-a) increases tumour formation in APC MIN/+ mice

Poster No: B94

Authors:
SHONDE A, BELL D, BENNETT A, HAWKEY C

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Accuracy of a regional colorectal cancer database: implications for the National Bowel Cancer Audit Programme

Poster No: B60

Authors:
KELLY M P, LAMAH M

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Accurate prediction of BRCA1 and BRCA2 heterozygous genotype using expression profiling after irradiation induced DNA damage

Poster No: A124

Authors:
KOTE-JARAI Z, MATTHEWS L, OSORIO A, SHANLEY S, GIDDINGS I, LOCKE I, EVANS G, WILLIAMS R, GIROLAMI M, CAMPBELL C, EELES R

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ACTIVATION OF CELL CYCLE CHECKPOINTS BY HUMAN PAPILLOMAVIRUS E4 PROTEIN

Poster No: B140

Authors:
KNIGHT G L, ROBERTS S

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Acute normal tissue reaction (moist desquamation) in patients with early breast cancer treated with 30Gy in 6 fractions over 15 days: Results of a pilot study

Poster No: C137

Authors:
DONOVAN E, EAGLE S, GOTHARD L, HAVILAND J, MARTIN S, ROSTOM A, TAIT D, YARNOLD J

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Acute toxicity of concomitant temozolamide in glioblastoma: experience of introducing a new treatment strategy to the clinic

Poster No: A167

Authors:
GREGORY DL, HOLLINGDALE AE, BURTON KE, JONES PH, BURNET NG, JEFFERIES SJ

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Adenovirus-directed enzyme prodrug therapy with E. coli nitroreductase (NTR) plus CB1954 enhances the effect of radiotherapy in vitro and in vivo

Poster No: A201

Authors:
WHITE CL, MENGHISTU TT, TWIGGER K, HARRINGTON K

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Adult Leydig-cell tumors of the testis caused by germline fumarate hydratase mutations

Poster No: A110

Authors:
CARVAJAL-CARMONA LG, BERNEY DM, TOMLINSON IPM

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AIDIT and IMPACT: strengthening research ties in Eastern Europe

Poster No: A115

Authors:
DOHERTY R, LUBINSKI J, ZIEBA K, MANGUOGLU E, LULECI G, CHRISTIE M, BANCROFT E, MITRA A, MORGAN S, EELES R

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Akt is a mediator of in vivo derived cisplatin resistance in isogenically paired ovarian cancer cell lines

Poster No: A41

Authors:
STRONACH| EA, CHEN M, BURCHETTE D, JOHNSON S, GABRA H

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Alkyladenine-DNA glycosylase (AAG) and alkylguanine-DNA alkyltransferase (MGMT) repair activity in peripheral blood mononuclear cells (PBMC) from lung cancer cases and cancer free controls

Poster No: BOA19

Authors:
CROSBIE PAJ, WATSON AJ, BARBER PV, AGIUS R, POVEY AC, MARGISON GP

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Allelic imbalances and chromosome 9p microdeletion demonstrated in cutaneous squamous cell carcinomas using single nucleotide polymorphism microarray analysis

Poster No: A108

Authors:
PURDIE K J, LAMBERT S R, HARWOOD C A, TEH M T, KELSELL D P, YOUNG B D, LEIGH I M, PROBY C M

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Allometric growth ratios in the mouse are independent of Igf2 allelic dosage

Poster No: A76

Authors:
BURNS JL, HALEY V, JACOBS C, HASSAN AB

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Amphiphilic hypercoiling polymer mediated delivery of novel cytotoxics

Poster No: CR-UK5

Authors:
TAVASSOLI M, FARZANEH F, SLATER N, LUXON B

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Amplification and gain of MDM4, a p53 regulator in urothelial cell carcinoma

Poster No: A89

Authors:
VEERAKUMARASIVAM A, SCOTT H E, WALLARD M J, WHITAKER H C, MILLS I G, ICHIMURA K, LEUNG H Y, COLLINS V P, NEAL D E, KELLY J D

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An ATM dependent checkpoint that inhibits spindle assembly

Poster No: A99

Authors:
SMITH E, COSTANZO V

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An Informatics Infrastructure to Support Tissue Banking and Research

Poster No: C13

Authors:
QUINLAN PR

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An investigation of the in vitro and in vivo pharmacology of a selective inhibitor of Aurora B kinase (AZD1152) in AML

Poster No: A214

Authors:
OKE A, PEARCE D, CRAFTER C, KEEN N, MUNDT K, ODEDRA R, WILKINSON RW, FOOT N, LISTER A, BONNET D, FITZGIBBON J, JOEL S

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Anaemia in Patients with Transitional Cell Carcinoma (TCC) of the Bladder Treated with Radiotherapy.

Poster No: B150

Authors:
JOYNSON C P, SUNDAR S, SYMONDS P

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Analysis of a metastasising sarcoma by quantitative light microscopy provides evidence of a role for protein 4.1B

Poster No: C45

Authors:
CAVANNA T, ZICHA D

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Analysis of Novel Gene Targets in Breast Cancer in Younger Women (

Poster No: C96

Authors:
LAMBE SM, SHAW JA, WALKER RA

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Analysis of recurrence rates two years after the treatment of superficial bladder cancer patients with intravesical EOquinTM (apaziquone, EO9).

Poster No: A219

Authors:
JAIN A, PURI R, LENAZ G, BEER M, PHILLIPS RM

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Analysis of the isochromosome 17q breakpoint in medulloblastomas

Poster No: C75

Authors:
MCCABE MG, LIU L, PEARSON DM, ICHIMURA K, ELLISON DW, CLIFFORD SC, COLLINS VP

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ANDROGEN REGULATION OF GONADOTROPIN RELEASING HORMONE TYPE II IN PROSTATE CANCER

Poster No: B24

Authors:
DARBY S, STOCKLEY J, ROBSON CN, EDMONSON RJ, LEUNG HY, GNANAPRAGASAM VJ

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Angiotensin receptor blockade resolves cancer induced wounding

Poster No: C47

Authors:
SMITH GR

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Anti-HPV vaccination: an exposition of the ethical issues

Poster No: B143

Authors:
DEY MP, DAWSON A

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Antisense RNA and DNA Methylation in Cancer

Poster No: C18

Authors:
CRUICKSHANKS H A, HASTINGS R K, BADGE R M, TUFARELLI C

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Anti-tumour activity, pharmacokinetic/pharmacodynamic relationships, and in vivo mechanism of action of AZD6244 (ARRY-142886), a potent and specific inhibitor of MEK1/2

Poster No: A185

Authors:
DAVIES B, LOGIE A, COCKERILL M, STEELE S, JENKINS R, MCKAY J, SMITH PD

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Applying a new paradigm of epidermal homeostasis to analyse the clonal evolution of cancer

Poster No: CR-UK11

Authors:
CLAYTON E, SIMONS B D, DOUPE D, WINTON D J, JONES P H

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Are Hip Fractures under-reported in Patients with Locally Advanced Anal Cancer treated with Chemoradiation (CRT)?

Poster No: B76

Authors:
SIZER B, MADHAVAN K, CONN P, ARULAMPALAM T, MOTSON R

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Are Lef/Tcf transcription factors involved in the progression of colorectal cancer?

Poster No: B77

Authors:
KAVANAGH C. L., WALLACE H. M., HOPPLER S. P.

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Are post-mortems in caner patients useful?

Poster No: A18

Authors:
HALL PS, BAVIDGE KL, CAREY F, RANKIN EM

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ASPECTS: A Study of Patients Experiences of TreatmentS

Poster No: A15

Authors:
AUDREY S, BLAZEBY J, ABEL J, CAMPBELL R

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Aspirin Induces Activation of NFkB Signalling and Apoptosis in Rectal Cancer Patients

Poster No: B71

Authors:
DIN FVN, REID K, MACDONALD AD, BRADY R, DUNLOP MG, STARK LA

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Assessing response to Transarterial Embolisation for HCC: A comparison of RECIST, EASL and AFP criteria.

Poster No: A59

Authors:
WOODWARD N, DAVIES N, PAPADOPOLOU A, BALLESFIN-SKELTON M, BURROUGHS A, MEYER T

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Assessing the role of Genetic Predisposition in patients with Multiple Primary Cancers.

Poster No: A82

Authors:
KOTNIS A, SARIN R, KANNAN S, MULHERKAR R

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Assessment of hypoxia associated markers in oesophagogastric cancer

Poster No: A53

Authors:
GRIFFITHS EA, PRITCHARD SA, WELCH IM, BISHOP PW, PRICE PM, WEST C

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Assessment of patient-scored normal tissue outcomes of prostate brachytherapy

Poster No: BOA8

Authors:
ANANDADAS C, ROUTLEDGE J, MANDALL P, SWINDELL R, LOGUE J, WYLIE J, DAVIDSON S

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Assessment of the radiosensitivity of rectal adenocarcinoma cells using the alkaline comet assay

Poster No: B95

Authors:
WATSON X, BRODERICK J, BURKE D, ROUTLEDGE M

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ASSOCIATION BETWEEN CELLULAR RNA SPLICING MACHINERY AND HUMAN PAPILLOMAVIRUS E4

Poster No: B145

Authors:
BELL I, MARTIN A, ROBERTS S

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Association between lung cancer risk and single nucleotide polymorphisms in the first intron and codon 178 of the DNA Repair gene O6-alkylguanine-DNA alkyltransferase

Poster No: A130

Authors:
POVEY AC, CROSBIE PAJ, PEARSON SJ, MCGOWN G, THORNCROFT MR, WATSON AJ, O'DONNELL PNS, BARBER PV, LEWIS SJ, HARRISON KL, AGIUS RM, DONNELLY D, MCELHINNEY RS, MCMURRY BH, SANTIBANEZ-KOREF MF, MARGISON GP

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Association of topoisomerase-1 (Topo1) with the efficacy of chemotherapy in a randomized trial for advanced colorectal cancer patients (FOCUS).

Poster No: BOA15

Authors:
BRAUN M.S., RICHMAN S.D., ADLARD J.W., DALY C., TURNER F., BARRETT J., PARMAR M., SELBY P., QUIRKE P., SEYMOUR M.T.

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Atl-1 protects S.pombe against the toxic effects of O6-alkylguanine in DNA

Poster No: A133

Authors:
WATSON A.J., BEGUM G., BUTT A., WHARTON S., PEARSON S.J., MARRIOTT A., WILLIAMS D., SHIBATA T., SANTIBANEZ-KOREF M., MARGISON G.P.

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ATM mutations occur in multiple myeloma at a low frequency

Poster No: A101

Authors:
AUSTEN B, BARONE C, RIEMAN A, BYRD P, BAKER C, STARCZYNSKI J, ENRIGHT H, QUINN J, PRATT G, STANKOVIC T, TAYLOR A