Future prospects for targeted therapies

Frank McCormick

Plenary Session: Future prospects for targeted therapies - The BACR Tom Connors Lecture

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Using cancer genomics to inform targeted drug development

Barbara Weber

Plenary Session: Using cancer genomics to inform targeted drug development - The Medical Research Council Lecture

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Nutritional and molecular biomarkers in cancer prevention

Shiela Bingham

Plenary Session: Nutritional and molecular biomarkers in cancer prevention - The Medical Research Council Lecture

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Interview Eight

Sandy Craine

Phase I clinical trials can benefit patients as well as test the safety of new cancer drugs.

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Interview Seven

Ian Judson

Phase I clinical trials can benefit patients as well as test the safety of new cancer drugs.

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Interview Six

Fran Balkwill

Immunotherapy has the potential to turn the immune system from a cancer helper into a cancer killer.

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Interview Five

Daniel Palmer

Dr Palmer explains how a genetically modified cold virus could help to treat cancer.

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Interview Four

Andy Gescher

The challenge in cancer prevention is translating research findings into public prevention measures.

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Interview Three

Guy Makin

A new drug has shown promising pre-clinical activity against cells from several types of children’s cancer.

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Interview Two

Graham Taylor and Neil Steven

Graham Taylor and Neil Steven: Research on a common virus has led to trials testing whether a vaccine can help treat cancer.

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Interview One

Catherine West

Dr West discusses her work trying to reduce the side effects of radiotherapy without reducing its effectiveness.

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Living beyond cancer: the challenges of surviorship care

Mary McCabe

Plenary Session: Living beyond cancer: the challenges of surviorship care - The Cancer Research UK Lecture

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Pancreatic cancer models and medicine

David Tuveson

Plenary Session: Pancreatic cancer models and medicine - The Cancer Research UK Lecture

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Interview Five

Max Parkin

Lifestyle changes could prevent one in ten cases of breast cancer by 2024 according to Prof Parkin.

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Interview Four

Paul Symonds

The identification of two genes may lead to a test that predicts adverse reactions to radiotherapy.

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Interview Three

Robert Clarke

Prof Clarke discusses his research into the regulation of breast cancer stem cells.

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Interview Two

Andrew Green

Dr Green explains what the identification of six distinct types of breast cancer might mean for patients.

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Interview One

Edzard Ernst

The eminent professor of complementary medicine talks about his work and the role of CAM in cancer treatment.

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Structure and mechanism of the HSP90 molecular chaperone

Laurence Pearl

Plenary Session: Structure and mechanism of the HSP90 molecular chaperone - The Leukaemia Research Fund Lecture

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Drugging the undruggable

Gregory Verdine

Plenary Session: Drugging the undruggable - The CR-UK London Research Institue Lecture

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Interview Three

Hilary Wareing

Second hand smoke exposure has fallen by 95 percent since the smoking ban was introduced in England.

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Interview Two

Amanda Ramirez

Informing older women about breast cancer raises awareness and could help to improve survival rates.

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Interview One

Prof Greg Verdine

Professor Verdine discusses his work developing a new class of cancer drugs targeting ’undruggable’ proteins

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Targeting epigenetic alterations in breast cancer

Nancy Davidson

Plenary Session: Targeting epigenetic alterations in breast cancer - The CR-UK Cambridge Research Institue Lecture

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Sensing of infection and anti-tumour immunity

Caetano Sousa

Plenary Session: Sensing of infection and anti-tumour immunity - The AstraZeneca Lecture

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Promoting early presentation with cancer

Amanda Ramirez

Plenary Session: Promoting early presentation with cancer - The Economic and Social Research Council Lecture

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Mouse Models for Cancer

Anton Berns

Plenary Session: Mouse Models for Cancer - The Beatson Institute for Cancer Research Lecture

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Drug Hunting to Beat Cancer

Prof. Roger Griffin

Roger Griffin’s Public Seminar and Open Forum

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Conference Introduction

Prof Mike Richards

In our final preview podcast, Professor Mike Richards,Chair of the the NCRI and National Cancer Director talks about his hopes for the conference this year, as well as highlighting the sessions he is most interested in hearing. But first, he discusses the progress that the UK has made in beating cancer over the past year. Professor Richards also addresses the issue of the cost of cancer drugs, now and in the future, as well as the importance of research.

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Roger Wilson on the 2007 Conference

Roger Wilson

Roger Wilson, outgoing chair of the NCRI Consumer Liaison Group, discusses the pivotal role of cancer patients and carers in the NCRI’s work, and the opportunities for them to meet senior researchers and learn more about cancer at the 2007 NCRI Cancer Conference. He talks about the session he is chairing on survival strategies, and looks forward to productive exchanges between patients, clinicians and scientists at the Conference this year.

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Drug Hunting To Beat Cancer

Roger Griffin

Roger Griffin, professor of medicinal chemistry at the Northern Institute for Cancer Research in Newcastle, speaks ahead of the Conference. Prof Griffin will be giving this year’s public lecture, and he explains why it’s important to engage the public with research. He also describes how basic science gets translated into potential new treatments, and tells us what he’s most looking forward to at the 2007 NCRI Cancer Conference.

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Combined Podcast

Various Speakers

• Molecule from Vegetables Could Help Treat Breast Cancer - Sheila Bingham and Margaret Manson
• 20 Pence Increase on a Pack of Cigarettes Best Way to Impact - Robert West

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Combined Podcast

Various Speakers

• Childhood Brain Tumour: New Drug Schedule Gives Better Results - Dr Richard Gilbertson
• Lung Cancer: Call for More Research Funding - Mr Peter Cardy
• Breast Cancer: New Risk Gene Identified - Jack Cuzick
• ‘Virtual Cancer Patient’ Could Help Tailor Therapy - Prof Nazneen Rahman

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Combined Podcast

Various Speakers

• Rectal Cancer Patients Survive Longer with Pre-Op Radiotherapy - Prof David Sebag-Montifiore
• Cancer Research Network Will Speed Scientific Progress into Patient Treatment - Prof Herbie Newell

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Mission possible: how we can beat cancer

Fran Balkwill

Fran Balkwill highlights her public lecture and explains why this is the golden age of cancer research

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Introducing the Programme

Alan Ashworth

Alan Ashworth describes the variety of cancer research to be presented in this year’s NCRI Conference

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Introducing the Conference

Mike Richards

Mike Richards, new Chairman of the NCRI, looks forward to this year’s Conference and discusses the future role of the NCRI

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RNA Interference May Rapidly Improve Cancer Treatments

Rene Bernards

RNA interference is a new technique that could lead to better and more personalised cancer therapy. René Bernards from the Netherlands Cancer Institute in Amsterdam told the NCRI Cancer Conference how it works, and has already been used to find a treatment for a benign skin tumour called cylindromatosis.

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New Tests, New Treatments: Better Survival Prospects in Pancreatic Cancer

John Neoptolemos

Pessimism about pancreatic cancer should now give way to optimism according to John Neoptolemos of Liverpool University and Margaret Tempero, from the UCSF Comprehensive Cancer Center in San Francisco who discussed latest progress in treatment and detection of this disease at the NCRI Cancer Conference.

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New Tests, New Treatments: Better Survival Prospects in Pancreatic Cancer

Margaret Tempero

Pessimism about pancreatic cancer should now give way to optimism according to John Neoptolemos of Liverpool University and Margaret Tempero, from the UCSF Comprehensive Cancer Center in San Francisco who discussed latest progress in treatment and detection of this disease at the NCRI Cancer Conference.

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DNA Chips Could Accelerate Search for Breast Cancer Genes

Bruce Ponder

It seems there are more genes involved in breast cancer than previously thought – but how can we find them? Bruce Ponder from the University of Cambridge told the NCRI Cancer Conference about a new DNA chip-based technique that could speed up the search.

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PARP Inhibitors: New Drugs Targeting DNA Repair Show Encouraging Results

Herbie Newell

A new class of drugs, called PARP inhibitors, could eventually lead to an improvement in the treatment of women with inherited breast and ovarian cancer. Herbie Newell, of the Northern Institute of Cancer Research in Newcastle, told the NCRI Cancer Conference about the work his group and others are doing.

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National Health Service Screening Initiative for Bowel Cancer

Wendy Atkin

60-69 year olds in Britain are to receive fecal occult blood testing to achieve a significant mortality improvement in bowel cancer. Wendy Atkin, of Imperial College, London, presented details at the NCRI Cancer Conference.

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Chemoprevention of Breast Cancer: A Strategy

Malcolm Pike

Breast cancer can be prevented by the manipulation of hormones, as explained at the first NCRI Cancer Conference by Malcolm Pike from the Keck School of Medicine in Los Angeles.

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The Hazards of Smoking and the Benefits of Stopping

Sir Richard Peto

50-year data on the hazards of smoking were presented at the NCRI Cancer Conference by Sir Richard Peto of Oxford University. Look closely at the picture: he wore Sir Richard Doll’s tie at the Birmingham meeting.

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Research Priorities as Identified by Patients

Jessica Corner & Jenny Walton

A group of cancer patients has conducted original research on priorities for cancer research as identified by patients rather than health-care professionals. At the NCRI Cancer Conference, Jessica Corner of the University of Southampton and cancer patient Jenny Walton presented surprising findings. Cancer survivor Jenny Walton is one of the study investigators looking into cancer research priorities from patients’ points of view.

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FOCUS Trial Could Influence UK Metastatic Colorectal Cancer Treatment

Will Steward

Results from the FOCUS study, which compared a number of treatment regimes for metastatic colorectal cancer, may suggest that standard practice in the UK should be changed. Will Steward of the University of Leicester discussed the data at the NCRI Cancer Conference.

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Inhibiting the Hsp90 Chaperone Protein: One Target Could Affect Many

Paul Workman

The protein Hsp90, which helps some other proteins to fold in the cell, seems an attractive target for cancer therapy because its inhibition could have multiple knock-on effects. Paul Workman of the Institute of Cancer Research in Sutton, Surrey explained some of the latest research to the NCRI Cancer Conference.

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NCRI Chairman Reflects on the Conference

Alex Markham

Alex Markham was Chairman of the NCRI at the time and is the Chief Executive of Cancer Research UK. He spoke briefly about his impressions of the first NCRI Cancer Conference

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