This report is based on the CTRad Methodology Workshop on „Approaches to the Evaluation of Rapidly Evolving Radiotherapy Technologies‟, funded by the Medical Research Council, and held on May 27th 2010 in London. …
A New Opportunity for Radiotherapy Research in the UK
'Radiotherapy contributes to the cure of 40% of patients diagnosed with cancer who survive 5 years or more, second only to surgery in its curative effectiveness [1].…
Executive summary of the ten-point action plan, 2008 (PDF)
'A 10-point action plan has been agreed by the NCRI Board and implementation began in the autumn of 2008.…
Rapid review of radiotherapy and associated radiobiology
'A group of research funders and experts met in April 2008 to consider and update the actions which had been undertaken as a result of NCRI’s first review of radiotherapy and associated radiobiology in 2003. …
NCRI’s first review of radiotherapy and associated radiobiology research, 2003 (PDF)
'The NCRI secretariat was asked to set up a review to review the current state of radiotherapy/radiobiology (RT/RB) research in the UK. …
CM-Path Cellular Pathology procedures with regards to release of research tissue samples (Word document)
'Cellular Pathology Departments act as a custodians of patient tissue samples held within diagnostic archives for NHS Trusts. Access, storage and archiving, must therefore be compliant with current good practice and legislative requirements.…
CM-Path SOP for Fresh Tissue Sampling (Word document)
'Molecular testing will become routine for many if not all pathology specimens in the future, as further genomic, transcriptomic, and proteomic changes present in disease can be harnessed for prognostication, therapeutic decision making, family screening, and prevention strategies. Accurate molecular testing is predicated upon well sampled, handled and preserved tissues, preferably fresh frozen. It is vital that fresh tissue sampling does not compromise the histological diagnosis and staging.…
CM-Path Recommendations for Molecular Testing and Research (Word document)
'The practice of molecular testing on pathological tissue samples is growing exponentially, but needs to be generalisable. The first step in this process is reducing variation introduced by processing of tissue from patient to Formalin Fixed Paraffin Embedded (FFPE) or Fresh Frozen (FF) sample. Low concordance rates of, for example, IHC are in part be due to variations in fixation media, time in fixation, processing protocols, and storage methods.…