A new £12 million initiative launched today (Wednesday) aims to tackle some of the major health problems in the UK,…
NCRI Partners flag £5 million for cancer research
'Funds of up to £5 million will be released over the next five years to improve the way cancer care…
New online tool will aid in cancer research collaboration and planning
'Cancer researchers around the world now have a powerful new tool at their fingertips that provides instant access to information…
NCRI announces new National Cancer Tissue Resource
'The creation of a national system to collect and analyse cancerous tissue through a virtual UK “tumour bank” will provide…
CM-Path Cellular Pathology procedures with regards to release of research tissue samples (Word document)
'Cellular Pathology Departments act as a custodians of patient tissue samples held within diagnostic archives for NHS Trusts. Access, storage and archiving, must therefore be compliant with current good practice and legislative requirements.…
CM-Path SOP for Fresh Tissue Sampling (Word document)
'Molecular testing will become routine for many if not all pathology specimens in the future, as further genomic, transcriptomic, and proteomic changes present in disease can be harnessed for prognostication, therapeutic decision making, family screening, and prevention strategies. Accurate molecular testing is predicated upon well sampled, handled and preserved tissues, preferably fresh frozen. It is vital that fresh tissue sampling does not compromise the histological diagnosis and staging.…
CM-Path Recommendations for Molecular Testing and Research (Word document)
'The practice of molecular testing on pathological tissue samples is growing exponentially, but needs to be generalisable. The first step in this process is reducing variation introduced by processing of tissue from patient to Formalin Fixed Paraffin Embedded (FFPE) or Fresh Frozen (FF) sample. Low concordance rates of, for example, IHC are in part be due to variations in fixation media, time in fixation, processing protocols, and storage methods.…